The British Journal of Children´s Diseases, 1915, Vol. 12 (Classic Reprint)
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Excerpt from The British Journal of Children´s Diseases, 1915, Vol. 12 Letoux has injected as much as 10 c.c. into each hemisphere. L. Delmas (´Presse Medicale,´ September the 17th, 1898) has not been successful with this method. In the case of a girl whom L. Ombredanne kindly trephined and injected for me, I was unfortunately unable to prevent a fatal issue(´Arch, de Med. des Enf.,´ August, 1899). The success of intracerebral injection, therefore, which requires the assistance of a good surgeon, is by no means invariable. The same is to be said of intra-spinal injection, which is a much simpler procedure, thanks to lumbar puncture. Both successes and failures have resulted from the use of this method. F. Peruzzi (´La Pediatria,´ July, 1908) cured a case of tetanus in a boy, aged 7 years, by eight intra-spinal injections of serum, each containing 10 c.c. (80 c.c. in all); the serum came from Berne. In five other cases treated in the same way the result was nil. After this failure, having two other cases of tetanus to treat, he injected at once into the spinal canal 30 c.c. of serum, and recovery took place. He therefore advocates massive intra-spinal injections of anti-tetanic serum. Subcutaneous injections of anti-tetanic serum have often been employed and in large doses. J. Galletly (´Brit. Med. Journ.,´ February the 18th, 1899) cured a boy, aged 8 years, by repeated injections of serum (240 c.c. in a fortnight); Murray (´Ind. Med. Record,´ March the 28th, 1914) cured a boy, who had contracted tetanus from a wound in the foot, by nine injections of anti-tetanic serum (one daily, in all 90 c.c). In Letoux´s case, that of a boy, aged 14 years, who had been given two intra-cerebral injections of 10 c.c, one must also take into account the numerous subcutaneous injections which were given (ten from May the 7th to May the 22nd, or 105 grm. of the anti-tetanic serum of the Institut Pasteur). V. Barachini (´Gazz. d. Osp.,´ January the 7th, 1900) cured a boy, aged 13 years, by two subcutaneous injections in the thigh of Tizzoni´s anti-tetanic serum (50 c.c. in all). This serum was employed at Pisa in the same manner in five other cases with successful results. S. H. Long (´Brit. Med. Journ.,´ November the 24th, 1900) cured a boy, aged 13 years, with thirteen subcutaneous and fifty-five rectal injections of anti-tetanic serum (680 c.c. in all). In a case of tetanus neonatorum in a female infant, aged 13 days, treated by J. MacCaw (´Brit. Med. Journ.,´ March the 30th, 1901) cure was obtained by two subcutaneous injections of anti-tetanic serum from the Institut Pasteur (3 c.c and 2 c.c. respectively). About the Publisher Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.
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