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Hidden Markov Models with Applications in Computational Biology




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79.90 EUR*
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Versand:0.00 EUR Versandkostenfrei innerhalb von Deutschland
Partner:buecher.de
Hersteller:Südwestdeutscher Verlag Für Hochschulschriften (Seifert, Michael)
Stand:2015-08-04 03:50:33

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Produktbeschreibung

Standard first-order Hidden Markov Models (HMMs) are very popular tools for the analysis of sequential data in applied sciences. HMMs are versatile and structurally simple models enabling probabilistic modeling based on a sound theoretical grounding. In contrast to the broad usage of first-order HMMs, applications of higher-order HMMs are very rare, but they have been proven to be powerful extensions of first-order HMMs including applications in speech recognition, image segmentation or computational biology. This book provides the first easily accessible and comprehensive extension of the algorithmic basics of first-order HMMs to higher-order HMMs coupled with practical applications in computational biology. The book starts with a theoretical part developing the algorithmic basics of higher-order HMMs and two novel model extensions (i) parsimonious higher-order HMMs and (ii) HMMs with scaled transition matrices. The second part considers applications of these models to the analysis of different DNA microarray data sets followed by a detailed discussion. The book addresses readers having basic knowledge on first-order HMMs interested to gain more insights on higher-order HMMs.


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